Glutathione is a tripeptide (cysteine, glycine, and glutamic acid) found in surprisingly high levels—5
millimolar—concentrations in most cells. This is the same concentration in cells as glucose, potassium,
and cholesterol! Considering the high level of metabolic activity required to produce glutathione, such a
high level underlines its importance. Glutathione is involved in the detoxification of both xenobiotic and
endogenous compounds. It facilitates excretion from cells (Hg), facilitates excretion from body (POPs,
Hg) and directly neutralizes (POPs, many oxidative chemicals). Glutathione facilitates the plasma
membrane transport of toxins by at least 4 different mechanisms, the most important of which is
formation of glutathione S-conjugates. Low levels of glutathione and/or transferase activity are also
associated with chronic exposure to chemical toxins and alcohol, cadmium exposure, AIDS/HIV, macular
degeneration, Parkinson’s disease, and other neurodegenerative disorders.
Reference:
Pizzorno J. Glutathione! Integr Med (Encinitas). 2014 Feb;13(1):8-12. PMID: 26770075; PMCID:
PMC4684116.

Weight 1 oz

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